郭祖奉，重庆医科大学生命科学研究院新靶标与化学干预研究中心特聘教授，博士生导师。于福州大学化学系获学士和硕士学位，香港科技大学获化学生物学博士学位，之后赴美国约翰霍普金斯大学医学院药理与分子科学系做博士后，2020年9月加入重庆医科大学。长期从事基于天然产物及其衍生物在抗肿瘤等领域的创新药物研发，发表SCI论文25篇，其中影响因子大于10的论文7篇，总引用次数1600余次，作为第一作者/通讯作者在Nat Chem、Angew Chem、Org Lett等高水平杂志发表论文6篇。申请国际专利7项，已获批5项，转化3项。Front Chem期刊编委，Signal Transduct Target Ther、Front Chem、Sci Rep、Med Chem等十多个SCI杂志审稿人。多次受邀在国内和国际学术会议上做学术报告。

代表性论文：

1. Z Guo^*, H Peng, Y Xie. BET family protein degraders poised to join the senolytic arsenal. Signal Transduct Target Ther. 2020, 5(1): 88-88.

2. Z Guo^#, SY Hong^#, J Wang^#, S Rehan, W Liu, H Peng, M Das, W Li, S Bhat, B Peiffe, BR Ullman, CM Tse, Z Tarmakova, CS Fischer, G Fischer, I Coe, VO Paavilainen, Zhaoli Sun, JO Liu^*. Rapamycin-inspired macrocycles with new target specificity. Nat Chem. 2019, 11(3): 254-263.

3. Z Guo^#, Z Cheng^#, J Wang^#, W Liu, H Peng, Y Wang, AVS Rao, RJ Li, X Ying, P Korangath, MV Liberti, Y Li, Y Xie, SY Hong, CS Fischer, G Fischer, JW Locasale, S Sukumar, H Zhu, JO Liu^*. Discovery of a potent GLUT inhibitor from a library of rapafucins by using 3D microarrays. Angew Chem Int Ed. 2019, 58(48): 17158-17162.

4. BJ Peiffer, L Qi, AR Ahmadi, Y Wang, Z Guo, H Peng, Z Sun^*, JO Liu^*. Activation of BMP signaling by FKBP12 ligands synergizes with inhibition of CXCR4 to accelerate wound healing. Cell Chem Biol. 2019, 26(5): 652-661.

5. B McClary^#, B Zinshteyn^#, ML Meyer^#, M Jouanneau, S Pellegrino, G Yusupova, A Schuller, JCP Reyes, J Lu, Z Guo, S Ayinde, C Luo, Y Dang, D Romo^*, M Yusupov^*, R Green^*, JO Liu^*. Inhibition of eukaryotic translation by the antitumor natural product agelastatin A. Cell Chem Biol. 2017, 24(5): 605-613.